Case Study 3: Criticality of High-Quality Curve Fitting—“Getting a Km,app” Isn’t as Simple as It May Seem
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Publisher
Springer US
Link
https://link.springer.com/content/pdf/10.1007/978-1-0716-1554-6_22
Reference6 articles.
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3. Atkins WM, Wang RW, Lu AY (2001) Allosteric behavior in cytochrome P450-dependent in vitro drug-drug interactions: a prospective based on conformational dynamics. Chem Res Toxicol 14:338–347
4. Koley AP, Buters JTM, Robinson RC et al (1995) CO binding kinetics of human cytochrome P-450 3A4: specific interaction of substrates with kinetically distinguishable conformers. J Biol Chem 270:5014–5018
5. Kumar S, Davydov RM, Halpert JR (2005) Role of cytochrome B5 in modulation peroxide-supported CYP3A4 activity: evidence for a conformational transition and cytochrome P450 heterogeneity. Drug Metab Dispos 33:1131–1136
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