Aortic Regurgitation: Review of the Diagnostic Criteria and the Management Guidelines

Author:

Malahfji MaanORCID,Saeed Mujtaba,Zoghbi William A.

Publisher

Springer Science and Business Media LLC

Subject

Cardiology and Cardiovascular Medicine

Reference26 articles.

1. Otto CM, Nishimura RA, Bonow RO, et al. 2020 ACC/AHA guideline for the management of patients with valvular heart disease: a report of the American College of Cardiology/American Heart Association Joint Committee on Clinical Practice Guidelines. J Am Coll Cardiol. 2021;77:e25–197.

2. Bonow RO, Carabello BA, Chatterjee K, et al. 2008 focused update incorporated into the ACC/AHA 2006 guidelines for the management of patients with valvular heart disease. Circulation. 2008. https://doi.org/10.1161/CIRCULATIONAHA.108.190748.

3. Bonow RO, Lakatos E, Maron BJ, Epstein SE. Serial long-term assessment of the natural history of asymptomatic patients with chronic aortic regurgitation and normal left ventricular systolic function. Circulation. 1991;84:1625–35.

4. •• Vejpongsa P, Xu J, Quinones MA, Shah DJ, Zoghbi WA. Differences in cardiac remodeling in left-sided valvular regurgitation: implications for optimal definition of significant aortic regurgitation. Cardiovasc Imaging. 2022;15:1730–1741. This CMR study demonstrated that patients with AR tend to have larger LV size and mass compared to patients with MR at similar Rvol and RF. Patients with AR who underwent surgery due to symptoms or LV remodeling had lower thresholds of Rvol and RF.

5. •• Malahfji M, Crudo V, Kaolawanich Y, et al. Association ofcardiac remodeling with aortic regurgitation outcomes: the AR Consortium of the SCMR Registry. J Am Coll Cardiol. 2023. https://doi.org/10.1016/J.JACC.2023.03.001. In this study of asymptomatic > moderate chronic AR patients with normal LVEF, quantitative CMR findings were associated with outcomes. LV volumes showed better prognostic value compared to LV diameters. The thresholds of Rvol and RF that demonstrated prognostic significance were also lower than thresholds recommended by guidelines.

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