Author:
Hellweg Christine Elisabeth,Arena Carmen,Baatout Sarah,Baselet Bjorn,Beblo-Vranesevic Kristina,Caplin Nicol,Coos Richard,Da Pieve Fabiana,De Micco Veronica,Foray Nicolas,Hespeels Boris,Heuskin Anne-Catherine,Kronenberg Jessica,Milojevic Tetyana,Miranda Silvana,Moris Victoria,Penninckx Sébastien,Radstake Wilhelmina E.,Rehnberg Emil,Rettberg Petra,Tabury Kevin,Van Doninck Karine,Van Hoey Olivier,Vogin Guillaume,Socol Yehoshua
Abstract
AbstractThe study of the biologic effects of space radiation is considered a “hot topic,” with increased interest in the past years. In this chapter, the unique characteristics of the space radiation environment will be covered, from their history, characterization, and biological effects to the research that has been and is being conducted in the field.After a short introduction, you will learn the origin and characterization of the different types of space radiation and the use of mathematical models for the prediction of the radiation doses during different mission scenarios and estimate the biological risks due to this exposure. Following this, the acute, chronic, and late effects of radiation exposure in the human body are discussed before going into the detailed biomolecular changes affecting cells and tissues, and in which ways they differ from other types of radiation exposure.The next sections of this chapter are dedicated to the vast research that has been developed through the years concerning space radiation biology, from small animals to plant models and 3D cell cultures, the use of extremophiles in the study of radiation resistance mechanisms to the importance of ground-based irradiation facilities to simulate and study the space environment.
Publisher
Springer International Publishing
Reference406 articles.
1. Lear J. Kepler’s dream. University of California Press; 1965.
2. Curie P. Oeuvres de Pierre Curie. Editions des Archives Contemporaines. 1984.
3. Todd P, Tobias CA, Silver IL. Current topics in space radiation biology. In: Tobias C, Todd P, editors. Space radiation biology and related topics. Academic Press; 1974. p. 1–18.
4. Millikan RA. Electrons (+ and -), protons, photons, neutrons, mesotrons and cosmic rays. University of Chicago Press; 1947.
5. Hess VF, Eugster JAG. Cosmic radiation and its biological effects. Fordham University Press; 1949.