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Incidence trends for common subtypes of T-cell lymphoma in Taiwan and the United States from 2008–2020

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Abstract

The incidence of T-cell lymphoma (TCL) has been continually increasing in Taiwan and the United States (US) in recent years. This epidemiological study using population-based registry data aimed to determine the incidence patterns of common subtypes of TCL in Taiwan from 2008–2020 and compare them with those in the US and the Asian/Pacific Islander (API) population. Subtypes included angioimmunoblastic T-cell lymphoma (AITL); extranodal NK/T-cell lymphoma, nasal or other type (ENKTL); peripheral T-cell lymphoma, not otherwise specified (PTCL-NOS); and anaplastic large cell lymphoma (ALCL). The total number of patients newly diagnosed with TCL during 2008–2020 was 4477, 3171, and 48,889 in Taiwan, API, and the US, respectively. Except the incidence rate of AITL in Taiwan, the incidence rates of these common TCL subtypes showed downward trends in all studied populations. There was also a significant increase in the relative frequency of AITL among TCL in Taiwan, with an annual percent change of 4.44 (p < 0.001), from 8.44% in 2002 to 20.63% in 2020. The rapid development of diagnostics may be the main factor contributing to this rise in incidence.

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All relevant data are within the manuscript and its Supporting Information files.

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Acknowledgements

The authors would like to thank Enago (http://www.enago.tw) for the English language review.

Funding

This work was supported by the grant EDAHP112031 from E-Da Hospital, Taiwan.

Author information

Authors and Affiliations

  1. Department of Radiation Oncology, E-Da Cancer Hospital, I-Shou University, Kaohsiung, Taiwan

    Chung-I Huang

  2. Department of Medical Imaging and Radiological Sciences, College of Medical Science and Technology, I-Shou University, Kaohsiung, Taiwan

    Chung-I Huang

  3. Division of Hematology-Oncology, Department of Internal Medicine, E-Da Hospital, I-Shou University, Kaohsiung, Taiwan

    Chien-Yu Ker, Hung-Ju Li, Yu-Ting Hsiao, Sheng-Fung Lin & Yu-Chieh Su

  4. Graduate Institute of Medicine, College of Medicine, I-Shou University, Kaohsiung, Taiwan

    Yu-Chieh Su

  5. School of Medicine, College of Medicine, I-Shou University, Kaohsiung, Taiwan

    Yu-Chieh Su

Authors
  1. Chung-I Huang
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  2. Chien-Yu Ker
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  3. Hung-Ju Li
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  4. Yu-Ting Hsiao
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  5. Sheng-Fung Lin
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Contributions

Conceptualization: Huang CI and Su YC. Data curation and formal analysis: Li HJ. Investigation and validation: Ker CY, Hsiao YT and Lin SF. Methodology and supervision: Lin SF and Su YC. Visualization and writing-original draft: Huang CI and Li HJ. Writing-review and editing: Lin SF and Su YC. All authors have read and agreed to the published version of the manuscript.

Corresponding authors

Correspondence to Sheng-Fung Lin or Yu-Chieh Su.

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12185_2024_3746_MOESM1_ESM.tif

Fig S1. Trend in age-standardized incidence rates of the nasopharyngeal carcinoma in Taiwan from 1995 to 2020 (TIF 214 kb)

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Huang, CI., Ker, CY., Li, HJ. et al. Incidence trends for common subtypes of T-cell lymphoma in Taiwan and the United States from 2008–2020. Int J Hematol (2024). https://doi.org/10.1007/s12185-024-03746-8

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  • DOI: https://doi.org/10.1007/s12185-024-03746-8

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