LEAP2 has antagonized the ghrelin receptor GHSR1a since its emergence in ancient fish
Author:
Funder
National Natural Science Foundation of China
Publisher
Springer Science and Business Media LLC
Subject
Organic Chemistry,Clinical Biochemistry,Biochemistry
Link
https://link.springer.com/content/pdf/10.1007/s00726-021-02998-6.pdf
Reference42 articles.
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3. Al-Massadi O, Müller T, Tschöp M, Diéguez C, Nogueiras R (2018) Ghrelin and LEAP-2: rivals in energy metabolism. Trends Pharmacol Sci 39:685–694
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5. Aslanipour B, Alan M, Demir I (2020) Decreased levels of liver-expressed antimicrobial peptide-2 and ghrelin are related to insulin resistance in women with polycystic ovary syndrome. Gynecol Endocrinol 36:222–225
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1. The ghrelin receptor GHSR has two efficient agonists in the lobe-finned fish Latimeria chalumnae;Biochemical and Biophysical Research Communications;2023-10
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3. LEAP2 is a more conserved ligand than ghrelin for fish GHSRs;Biochimie;2023-06
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