The osteoporosis susceptibility SNP rs188303909 at 2q14.2 regulates EN1 expression by modulating DNA methylation and E2F6 binding-Reference-Cited by-同舟云学术

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The osteoporosis susceptibility SNP rs188303909 at 2q14.2 regulates EN1 expression by modulating DNA methylation and E2F6 binding

Published:2023-12-28 Issue: Volume: Page:
ISSN:0946-2716
Container-title:Journal of Molecular Medicine
language:en
Short-container-title:J Mol Med

Author:

Wang Ya,Huang Xinyao,Zhang Qiongdan,Cheng Chen,Qin Zixuan,Lu Li,Huang Qingyang^ORCID

Funder

National Natural Science Foundation of China

Fundamental Research Funds for the Central Universities

Hubei Key Laboratory of Genetic Regulation and Integrative Biology

Zhejiang Provincial Natural Science Foundation

Publisher

Springer Science and Business Media LLC

Subject

Genetics (clinical),Drug Discovery,Molecular Medicine

Link

https://link.springer.com/content/pdf/10.1007/s00109-023-02412-6.pdf

Reference46 articles.

1. Ralston S-H, Uitterlinden A-G (2010) Genetics of osteoporosis. Endocr Rev 31(5):629–662

2. Yang T-L, Shen H, Liu A, Dong S-S, Zhang L, Deng F-Y, Zhao Q, Deng H-W (2020) A road map for understanding molecular and genetic determinants of osteoporosis. Nat Rev Endocrinol 16(2):91–103

3. Zhu DL, Chen XF, Zhou XR, Hu SY, Tuo XM, Hao RH, Dong SS, Jiang F, Rong Y, Yang TL (2022) An osteoporosis susceptibility allele at 11p15 regulates SOX6 expression by modulating TCF4 chromatin binding. J Bone Miner Res

4. Chen X-F, Zhu D-L, Yang M, Hu W-X, Duan Y-Y, Lu B-J, Rong Y, Dong S-S, Hao R-H, Chen J-B (2018) An osteoporosis risk SNP at 1p36. 12 acts as an allele-specific enhancer to modulate LINC00339 expression via long-range loop formation. Am J Hum Genet 102(5):776–793

5. Ye W, Wang Y, Hou S, Mei B, Liu X, Huang H, Zhou Q, Niu Y, Chen Y, Zhang M (2021) USF3 modulates osteoporosis risk by targeting WNT16, RANKL, RUNX2, and two GWAS lead SNPs rs2908007 and rs4531631. Hum Mutat 42(1):37–49

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1. New insights into dairy management and the prevention and treatment of osteoporosis: The shift from single nutrient to dairy matrix effects—A review;Comprehensive Reviews in Food Science and Food Safety;2024-06-07

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