Targeted inhibition of histone deacetylase leads to suppression of Ewing sarcoma tumor growth through an unappreciated EWS-FLI1/HDAC3/HSP90 signaling axis-Reference-Cited by-同舟云学术

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Targeted inhibition of histone deacetylase leads to suppression of Ewing sarcoma tumor growth through an unappreciated EWS-FLI1/HDAC3/HSP90 signaling axis

Published:2019-04-25 Issue:7 Volume:97 Page:957-972
ISSN:0946-2716
Container-title:Journal of Molecular Medicine
language:en
Short-container-title:J Mol Med

Author:

Ma Yan,Baltezor Michael,Rajewski Lian,Crow Jennifer,Samuel Glenson,Staggs Vincent S.,Chastain Katherine M.,Toretsky Jeffrey A.,Weir Scott J.,Godwin Andrew K.

Funder

MCA Partners Advisory Board

Braden's Hope for Childhood Cancer Foundation

the Kansas Bioscience Authority Eminent Scholar Program

Publisher

Springer Science and Business Media LLC

Subject

Genetics(clinical),Drug Discovery,Molecular Medicine

Link

http://link.springer.com/content/pdf/10.1007/s00109-019-01782-0.pdf

Reference49 articles.

1. Balamuth NJ, Womer RB (2010) Ewing’s sarcoma. Lancet Oncol 11:184–192

2. Jain S, Kapoor G (2010) Chemotherapy in Ewing’s sarcoma. Indian J Orthop 44:369–377

3. Perkins SM, Shinohara ET, DeWees T, Frangoul H (2014) Outcome for children with metastatic solid tumors over the last four decades. PLoS One 9:e100396. https://doi.org/10.1371/journal.pone.0100396

4. Womer RB, West DC, Krailo MD, Dickman PS, Pawel BR, Grier HE, Marcus K, Sailer S, Healey JH, Dormans JP, Weiss AR (2012) Randomized controlled trial of interval-compressed chemotherapy for the treatment of localized Ewing sarcoma: a report from the Children’s Oncology Group. J Clin Oncol 30:4148–4154

5. Hamilton SN, Carlson R, Hasan H, Rassekh SR, Goddard K (2017) Long-term outcomes and complications in pediatric Ewing sarcoma. Am J Clin Oncol 40:423–428

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