Precision-cut liver slices as an alternative method for long-term hepatotoxicity studies
Author:
Publisher
Springer Science and Business Media LLC
Subject
Health, Toxicology and Mutagenesis,Toxicology,General Medicine
Link
https://link.springer.com/content/pdf/10.1007/s00204-020-02861-9.pdf
Reference26 articles.
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2. Bigaeva E, Gore E, Simon E, Zwick M, Oldenburger A, de Jong KP et al (2019) Transcriptomic characterization of culture-associated changes in murine and human precision-cut tissue slices. Arch Toxicol 93(12):3549–3583. https://doi.org/10.1007/s00204-019-02611-6
3. Bosgra S, Westerhout J (2015) Interpreting in vitro developmental toxicity test battery results: The consideration of toxicokinetics. Reprod Toxicol 1(55):73–80. https://doi.org/10.1016/j.reprotox.2014.11.001
4. de Graaf IA, Olinga P, de Jager MH, Merema MT, de Kanter R, van de Kerkhof EG et al (2010) Preparation and incubation of precision-cut liver and intestinal slices for application in drug metabolism and toxicity studies. Nat Protoc 5(9):1540–1551. https://doi.org/10.1038/nprot.2010.111
5. Elferink MG, Olinga P, van Leeuwen EM, Bauerschmidt S, Polman J, Schoonen WG et al (2011) Gene expression analysis of precision-cut human liver slices indicates stable expression of ADME-Tox related genes. Toxicol Appl Pharmacol 253(1):57–69. https://doi.org/10.1016/j.taap.2011.03.010
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