Intestinal and hepatic biotransformation of pyrrolizidine alkaloid N-oxides to toxic pyrrolizidine alkaloids
Author:
Funder
Research Grant Council of Hong Kong
Publisher
Springer Science and Business Media LLC
Subject
Health, Toxicology and Mutagenesis,Toxicology,General Medicine
Link
http://link.springer.com/content/pdf/10.1007/s00204-019-02499-2.pdf
Reference61 articles.
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3. Bull LB, Dick AT, McKenzie JS (1958) The acute toxic effects of heliotrine and lasiocarpine, and their N-oxides, on the rat. J Pathol Bacteriol 75:17–25
4. Cao Y, Colegate SM, Edgar JA (2008) Safety assessment of food and herbal products containing hepatotoxic pyrrolizidine alkaloids: interlaboratory consistency and the importance of N-oxide determination. Phytochem Anal 19:526–533
5. Chauvin P, Dillon JC, Moren A (1994) An outbreak of Heliotrope food poisoning, Tadjikistan, November 1992–March 1993. Sante 4:263–268
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