Aristolochic acid IVa forms DNA adducts in vitro but is non-genotoxic in vivo
Author:
Funder
National Natural Science Foundation of China
Publisher
Springer Science and Business Media LLC
Subject
Health, Toxicology and Mutagenesis,Toxicology,General Medicine
Link
https://link.springer.com/content/pdf/10.1007/s00204-021-03077-1.pdf
Reference48 articles.
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2. Balachandran P, Wei F, Lin RC, Khan IA, Pasco DS (2005) Structure activity relationships of aristolochic acid analogues: toxicity in cultured renal epithelial cells. Kidney Int 67(5):1797–1805. https://doi.org/10.1111/j.1523-1755.2005.00277.x
3. Chan W, Cui L, Xu G, Cai Z (2006) Study of the phase I and phase II metabolism of nephrotoxin aristolochic acid by liquid chromatography/tandem mass spectrometry. Rapid Commun Mass Spectrom 20(11):1755–1760. https://doi.org/10.1002/rcm.2513
4. Chan CK, Liu Y, Pavlovic N, Chan W (2019) Aristolochic acids: newly identified exposure pathways of this class of environmental and food-borne contaminants and its potential link to chronic kidney diseases. Toxics 7(1):14. https://doi.org/10.3390/toxics7010014
5. Chen CH, Dickman KG, Moriya M et al (2012) Aristolochic acid-associated urothelial cancer in Taiwan. Proc Natl Acad Sci USA 109(21):8241–8246. https://doi.org/10.1073/pnas.1119920109
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1. Novel monoclonal antibody-based sensitive enzyme-linked immunosorbent assay and rapid immunochromatographic strip for sensitive detecting aristolochic acid I in herbal remedies;Microchemical Journal;2023-08
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