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Physiologically based pharmacokinetic model combined with reverse dose method to study the nephrotoxic tolerance dose of tacrolimus

  • Published:2023-08-12 Issue:10 Volume:97 Page:2659-2673
  • ISSN:0340-5761
  • Container-title:Archives of Toxicology
  • language:en
  • Short-container-title:Arch Toxicol

Author:

Cai Limin,Ke Meng,Wang Han,Wu Wanhong,Lin Rongfang,Huang Pinfang,Lin CuihongORCID

Funder

Fujian Provincial Department of Science and Technology

Publisher

Springer Science and Business Media LLC

Subject

Health, Toxicology and Mutagenesis,Toxicology,General Medicine

Reference63 articles.

1. Abdullah R, Alhusainy W, Woutersen J, Rietjens IMCM, Punt A (2016) Predicting points of departure for risk assessment based on in vitro cytotoxicity data and physiologically based kinetic (PBK) modeling: the case of kidney toxicity induced by aristolochic acid I. Food Chem Toxicol 92:104–116. https://doi.org/10.1016/j.fct.2016.03.017

2. Algharably EAE-H, Di Consiglio E, Testai E, Kreutz R, Gundert-Remy U (2021) Prediction of the dose range for adverse neurological effects of amiodarone in patients from an in vitro toxicity test by in vitro-in vivo extrapolation. Arch Toxicol 95:1433–1442. https://doi.org/10.1007/s00204-021-02989-2

3. Balazki P, Schaller S, Eissing T, Lehr T (2018) A quantitative systems pharmacology kidney model of diabetes associated renal hyperfiltration and the effects of SGLT inhibitors. CPT Pharmacometrics Syst Pharmacol 7:788–797. https://doi.org/10.1002/psp4.12359

4. Balhara A, Ladumor MK, Nankar RP, Syed SD, Giri S, Prasad B, Singh S (2022) Exploration of the plausible mechanism of ethambutol induced ocular toxicity by using proteomics informed physiologically based pharmacokinetic (PBPK) modeling. Pharm Res 39:677–689. https://doi.org/10.1007/s11095-022-03227-9

5. Barter ZE, Tucker GT, Rowland-Yeo K (2013) Differences in cytochrome P450-mediated pharmacokinetics between chinese and caucasian populations predicted by mechanistic physiologically based pharmacokinetic modelling. Clin Pharmacokinet 52:1085–1100. https://doi.org/10.1007/s40262-013-0089-y

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