Multi-omics analyses provide novel biological insights to distinguish lobular ductal types of invasive breast cancers

Author:

Sivadas AmbilyORCID,Kok Victor C.ORCID,Ng Ka-LokORCID

Funder

Ministry of Science and Technology, Taiwan

Asia University Taiwan

The Wellcome Trust DBT India Alliance

Publisher

Springer Science and Business Media LLC

Subject

Cancer Research,Oncology

Reference62 articles.

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2. Pestalozzi BC, Zahrieh D, Mallon E, Gusterson BA, Price KN, Gelber RD, Holmberg SB, Lindtner J, Snyder R, Thürlimann B, Murray E, Viale G, Castiglione-Gertsch M, Coates AS, Goldhirsch A (2008) Distinct clinical and prognostic features of infiltrating lobular carcinoma of the breast: combined results of 15 International Breast Cancer Study Group clinical trials. J Clin Oncol 26:3006–3014. https://doi.org/10.1200/jco.2007.14.9336

3. Weigelt B, Geyer FC, Natrajan R, Lopez-Garcia MA, Ahmad AS, Savage K, Kreike B, Reis-Filho JS (2010) The molecular underpinning of lobular histological growth pattern: a genome-wide transcriptomic analysis of invasive lobular carcinomas and grade- and molecular subtype-matched invasive ductal carcinomas of no special type. J Pathol 220:45–57. https://doi.org/10.1002/path.2629

4. Berx G, Cleton-Jansen AM, Strumane K, de Leeuw WJ, Nollet F, van Roy F, Cornelisse C (1996) E-cadherin is inactivated in a majority of invasive human lobular breast cancers by truncation mutations throughout its extracellular domain. Oncogene 13:1919–1925

5. Chen F, Ding K, Priedigkeit N, Elangovan A, Levine KM, Carleton N, Savariau L, Atkinson JM, Oesterreich S, Lee AV (2020) Single-cell transcriptomic heterogeneity in invasive ductal and lobular breast cancer cells. Cancer Res 81:268–281. https://doi.org/10.1158/0008-5472.CAN-20-0696

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