ISP - IFRO SLICE PROTEIN

Author:

Costa Guimarães Dyuly KelryORCID,Linhares de Araújo Micaely Raira,Zaire dos Santos Kethelin Vitória,Lopes de Barros Henrique,Rodrigues Miranda MarcioORCID,Silva Kaio Alexandre daORCID

Abstract

Macromolecules are proteins formed by amino acids joined by peptide bonds, and can be described in different structural levels: primary, secondary, tertiary and quaternary. It’s possible to extract a small part of the three dimensional structure of the protein to be used as a ligand. However, the extraction of fragments by experimental methods is expensive and time-consuming. In this context, the development of a web service to extract fragments of three-dimensional proteins makes the process more assertive and less costly. The methods used for the development of the protein slicer web service were the Python programming language, and the Javascript, PHP and HTML languages are being used. And for the testing of the system, three-dimensional structures of proteins present in the RCSB Protein Data Bank (RCSB PDB) were used.

Publisher

International Journal for Innovation Education and Research

Subject

General Medicine

Reference12 articles.

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3. COLHADO, Orlando Carlos Gomes; BOEING, Marcelo; ORTEGA, Luciano Bornia. Toxina botulínica no tratamento da dor. Revista Brasileira de Anestesiologia, v. 59, p. 366-381, 2009.

4. de Mello Sposito, Maria Matilde. "Toxina Botulínica do Tipo A: mecanismo de ação." Acta fisiátrica 16.1 (2009): 25-37.

5. LODISH, H. et al. Biologia celular e molecular. 7. ed. Porto Alegre: Artmed, 2014.

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