ANALYSIS OF POST MSICS IOP RISE WITH 2%HPMC AND 1% SODIUM HYALURONATE OVDs - a comparative study

Abstract

Background. Elevated IOP is the most frequent postoperative complication after cataract surgery and consequences of raised IOP lead to sight threatening problem. Intraocular pressure spikes of 30 mm HG or higher in the early period after cataract surgery causes pain, corneal epithelial edema, and damage to optic disc. The main cause of postoperative IOP increase is that the viscoelastic agent remains in the eye, which causes a mechanical obstruction of trabecular meshwork . To compare theAims and objectives. effect of two OVDs (2% HPMC and 1% Sodium Hyaluronate) on Intraocular pressure after MSICS. This is a prospectiveStudy design. observational study of 8 months duration in a tertiary hospital of Eastern India. 100 consecutive patients above the age 50 years havingMethods. age related cataract planned for elective cataract surgery will be included in this study. 50 consecutive patients were assigned to receive Hydroxypropyl methylcellulose(2%) and remaining 50 patients were assigned to receive Sodium hyaluronate (1%) during surgery. The IOP was measured 6 hours,24 hours and 1 week after surgery and the ndings were noted. After the study period the collected data was analyzed by standard statistical tools. .Mean IOP increased by 4.08 mm of Hg in the group receiving 2% HPMC and by 8.2 mm of Hg in patientsResults receiving 1% Sodium Hyaluronate. In both HPMC and Sodium Hyaluronate group the rise of the IOP in 6 hour post operative period was found to be signicantly higher (p<0.05) than the pre operative IOP value. But the post operative 6 hour mean IOP rise was 4.32 mmHg more in the Sodium Hyaluronate group(8.2mm Hg) than the HPMC group (4.08 mmHg) . 24 hours and 1 week post-operatively the rise in mean IOP was found to be not signicantly different from each other. These ndings indicate that 1% Sodium Hyaluronate causes a signicantlyConclusion : higher IOP rise than 2% HPMC in the early post operative period.But 24 hours and 1 week post-operatively the rise in mean IOP was insignicant in both the group.