A CASE REPORT AND LITERATURE REVIEW: PRIMARY CARCINOMA OF LACRIMAL GLAND TREATED WITH ADJUVANT CHEMO- RADIATION.-Reference-Cited by-同舟云学术

A CASE REPORT AND LITERATURE REVIEW: PRIMARY CARCINOMA OF LACRIMAL GLAND TREATED WITH ADJUVANT CHEMO- RADIATION.

Published:2022-07-01 Issue: Volume: Page:9-10
ISSN:
Container-title:INTERNATIONAL JOURNAL OF SCIENTIFIC RESEARCH
language:en
Short-container-title:ijsr

Author:

S Thamizholi¹,T Kannan²,Kalita Lachit³,Chourasia Ranu⁴

Affiliation:

1. Consultant Clinical Oncologist, Assam Cancer Care Foundation, Barpeta.

2. Consultant Medical Oncologist, Assam Cancer Care Foundation, Barpeta.

3. Fellow Onco-pathology, Assam Cancer Care Foundation, Barpeta.

4. Ph.D. Scholar, VISTAS, Chennai.

Abstract

Primary Sebaceous Carcinoma of Lacrimal Gland, possibly arising from heterotopic sebaceous tissue, is extremely rare and must be differentiated from secondary invasion of the Orbit by a primary Eyelid tumor/metastatic spread from other areas of the body. It is known to be aggressive So, delay in diagnosis can increase the chance of local recurrence and metastasis. In this article we report a case of Primary Sebaceous Carcinoma of the lacrimal gland, who underwent surgery with positive margin received Adjuvant radiotherapy in our Institute. A 55-year-OldCASE REPORT: Lady presented with Left eyelid swelling. MRI ORBITS & PNS reveals malignant mass of approx. 4.3 X 3.8 cm size in superior & temporal aspect of the left Orbit arising from the left upper eyelid compressing left globe and inseparable from the left lacrimal gland with approx. 2.3X 1.5 cm sized enlarged left Pre- auricular Node. No optic nerve encasement, Orbital wall Destruction & Extension to adjacent paranasal sinuses is seen. CECT Thorax & Whole abdomen – Normal. FNAC from eyelid swelling & Pre- Auricular Node S/o Sebaceous Carcinoma with metastasis. Patient underwent left Orbital Exenteration + left supercial parotid split skin graft. HPE show the tumor mass of size 4.5 X 4X 3 cm, completely replacing tarsal plate of eyelid & tumor mass show a highly inltrative malignant tumor with morphology consistent with sebaceous carcinoma with positive margin and tissue from left parotid show inltration by the sebaceous carcinoma (Possibly metastasis to the Intra-parotid node with extra nodal extension). Patient received Adjuvant/post op Chemoradiation 60 Gy/30#/ 6weeks/Rapid Arc technique with weekly 6 cycles chemotherapy Inj. Cisplatin. Patient requires close monitoring for any sign of recurrence / Distant metastasis. A Rare case report of sebaceousCONCLUSION: carcinoma of the Lacrimal Gland which requires appropriate evaluation & management for better prognosis.

Publisher

World Wide Journals

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