HIGH NORMOTENSION IS ASSOCIATED WITH METABOLIC SYNDROME BUT NOT NON-FATAL CARDIOVASCULAR EVENTS

Abstract

Introduction: Due to the blood pressure was one of the diagnosis criteria in MetS, blood pressure was increased with aging. Whether the increased blood pressure in normotensive range is still associated with MetS and more important, cardiovascular disease, we conducted a 4-year longitudinal observation study to elucidate these association. Methods: a total 9,133 subjects were qualied for analysis. We further grouped these subjects into SBP1 to SBP3 and DBP1 and DBP3. SBP1 was SPB < 99 mmHg, SBP2 was SPB >100, < 109 mmHg, SBP3 was SPB >110, < 119 mmHg. DBP1 was DPB < 59 mmHg, DBP2 was DPB >60, < 69 mmHg, DBP3 was DPB >70, < 79 mmHg. Results: After 4 years of follow-up, SBP3 group still had higher risk of developing future MetS but not future non-fatal cardiovascular diseases. However, SBP3 group in female fail to show signicant in future MetS. In addition, both SPB3 group and DPB3 group fail to show signicant in developing future non-fatal cardiovascular diseases.Kaplan-Meier estimates showed both SPB and DBP groups showed signicant difference in developing future MetS but not in developing future non-fatal cardiovascular diseases. Conclusion: In conclusion, high normotensive bloop pressure is still a risk for having MetS in the future but not non-fatal cardiovascular diseases. DBP looks more sensitive than SBP in the future events development in the elderly.