“A COMPARATIVE EVALUATION OF EFFECT OF INTRA ARTICULAR FENTANYL VERSUS DEXMEDETOMIDINE AS ADJUVANT TO ROPIVACAINE ON POST OPERATIVE PAIN IN KNEE ARTHROSCOPIC SURGERIES”

Author:

Noorani Sania1,Rastogi Bhawana2,Situ Situ3,Rastogi Avinash4,Chaudhary Garima5,Chaudhary Gaurav5

Affiliation:

1. Senior resident, Department of anaesthesiology and critical care, Subharti Medical College, Swami Vivekanand Subharti University, NH-58 Bye Pass Road, Meerut-UP, India

2. Professor and head, Department of Anaesthesiology and Critical care, Subharti Medical College, Swami Vivekanand Subharti University, NH-58 Bye Pass Road, Meerut-UP, India

3. Assistant professor, Department of anaesthesiology and critical care, Subharti Medical College, Swami Vivekanand Subharti University, NH-58 Bye Pass Road, Meerut-UP, India

4. Professor Department of Orthopedics, Subharti Medical College, Swami Vivekanand Subharti University, NH-58 Bye Pass Road, Meerut-UP, India

5. Junior resident, Department of anaesthesiology and critical care, Subharti Medical College, Swami Vivekanand Subharti University, NH-58 Bye Pass Road, Meerut-UP, India

Abstract

Background: Knee arthroscopy involves good repair of knee ligaments and menisci with minimal injuries but with variable degree of post operative pain. This pain can be minimal in some but can be very distressing in others. This study aims at evaluating effect of intra articular fentanyl versus dexmedetomidine as adjuvant to ropivacaine on post operative pain in knee arthroscopic surgeries. Ninety patients of ASA Class I Materials and Methods: /II, aged 20–60 years posted for arthroscopic knee surgery were randomly divided into Group R (control group),Group RF(fentanyl) and Group RD (dexmedetomidine) with 30 patients in each group. Anaesthetic technique used was spinal anaesthesia in all patients. Group I patients received Ropivacaine 0.75% 22 ml , group II received Ropivacaine 0.75% 20 ml +Fentanyl 1mcg/kg and Group III received 1 µg/kg dexmedetomidine diluted to 20 ml Ropivacaine 0.75% via intra-articular route at end of procedure. VAS score for 24 h, time to rst rescue analgesia and total dose of analgesic required in each group was evaluated. Results: VAS scores were signicantly lower in Group III, time to rst analgesic requirement was highest in group III (412.2±34.9mins) and lowest in group I (280.4±18.8mins), P value 0.002. Total dose of analgesic used in Group III (166.667±47.946 mg) patients was signicantly lesser compared to patients in Group I (273.33±44.978 mg) and group II (183.33±46.113 mg), P value 0.0226. Intra-articular dexmedetomidine as adjuvant t Conclusion: o 0.75% ropivacaine is effective in providing prolonged postoperative analgesia and decreases total analgesic requirements without any signicant side effects after arthroscopic knee procedures.

Publisher

World Wide Journals

Subject

Atmospheric Science,General Environmental Science,Renewable Energy, Sustainability and the Environment,Paleontology,Stratigraphy,Global and Planetary Change,Paleontology,Stratigraphy,Global and Planetary Change,Atmospheric Science,Environmental Science (miscellaneous),Global and Planetary Change,Management, Monitoring, Policy and Law,Atmospheric Science,General Environmental Science,Environmental Chemistry,Management, Monitoring, Policy and Law,Atmospheric Science,Geography, Planning and Development,Global and Planetary Change,Atmospheric Science,Global and Planetary Change,Atmospheric Science,Global and Planetary Change,Pharmacology,Toxicology

Reference20 articles.

1. Muneer K, Khurshid H, Naqashbandi JI. Efficacyofintra-articular dexmedetomidine for postoperative analgesia in arthroscopic knee surgery done under spinal anesthesia.Indian J Pain.2016;30:96-100.

2. Miller RD, Eriksson IL, Fleisher AL, Weiner-Kronish JP, Young WL. Miller’s anesthesia. In: Michael KU, editor. Anesthesia for Orthopedic Surgery. 7th ed. Philadelphia: Churchill Livingstone; 2010. 2249 50.

3. Al Metwalli RR, Mowafi HA, Ismail SA, Siddiqui AK, Al Ghamdi AM, Shafi MA, et al. Effect of intra articular dexmedetomidine on postoperative analgesia after arthroscopic knee surgery. Br J Anaesth. 2008;101:395 9.

4. Dye SF, Vaupel GL, Dye CC. Conscious neurosensory mapping of the internal structures of the human knee without intraarticular anesthesia. Am J Sports Med. 1998; 26: 773 – 7.

5. El-Hamamsy M, Dorgham D. Intra-articular adjuvant analgesics following knee arthroscopy: comparison between dexmedetomidine and fentanyl. Res J Med MedSci. 2009; 4: 355–60.

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