Affiliation:
1. Junior Resident, Radiodiagnosis ,GMC Aurangabad
2. Junior Resident, Radiodiagnosis, GMC Aurangabad
3. Prof & HOD, Radiodiagnosis, GMC Aurangabad
Abstract
Background: COVID-19 is an infection that has widely and rapidly spread all over the world. The clinical presentations being asymptomatic
carriers to requiring assisted ventilatory support with increased mortality. Clinical parameters like oxygen saturation, respiratory rate and
laboratory parameters like CRP, ferritin, d-dimer etc have been used to classify patients according to disease severity. CT chest manifestations in
COVID pneumonia resemble to those seen in any viral infection To establish Aims & Objectives: correlation between CT severity score and
Clinico-laboratory parameters in RTPCR proven positive COVID 19 patients and study the role of HRCT chest in clinical management of COVID
19 patients. We collected clinical and laboratory data for analysis of pati Materials and Methods: ents who had RTPCR positive COVID-19
infection and underwent a chest HRCT chest scan with 128 slice CT scanner in our tertiary care hospital. Three radiologists evaluated the scan to
determine the CT severity score (CTSS) and studied typical, intermediate & atypical imaging features in each patient and assigned CT severity
score for oxygen dependency , the patients were classied radiologically into negative, mild and severe disease The statistical analysis was
performed using IBM SPSS and Microsoft excel. Descriptive statistics of patients clinical, and laboratory results were reported as numbers and
relative frequencies. Frequencies of CT scores were calculated and compared with other clinical variables. The Pearson correlation coefcient test
was used for correlations, and p value less than 0.01 was dened statistically signicant. A Chi square analysis was done to establish relationship
between CTSS oxygen dependency, remdesivir and steroid usage. CTSS and oxygen dependency had Results: strong negative Pearson's
association. Severe CTSS (10 & above) had 98.3% sensitivity in relation to requirement of O2 in patients, with high negative predictive value
99.3%. Positive likelihood ratio 4.33, negative likelihood ratio 0.02. The Pearson's correlation coefcient showed moderately positive signicant
association between CTSS & S.CRP levels, CTSS & S.ferritin level. Signicant P value is seen in severe patients having higher CTSS, treated with
steroids and remdesivir. A CT-SS score less than 10 could rule out oxygen dependency Conclusion: and severe form of disease with a high negative
predictive value of 99.3% in our cohort. Clinical intervention in patients according to CT severity score can be of value as evident by signicant
association demonstrated in our study.
Subject
History,Immunology,Immunology and Allergy,Pulmonary and Respiratory Medicine,Public Health, Environmental and Occupational Health,Health Policy,Law,Sociology and Political Science,Literature and Literary Theory,Linguistics and Language,Language and Linguistics,General Engineering,Literature and Literary Theory,Linguistics and Language,Language and Linguistics,Literature and Literary Theory,History,Cultural Studies,Political Science and International Relations