THROMBOTIC THROMBOCYTOPENIC PURPURA (TTP) - AN UPDATED REVIEW-Reference-Cited by-同舟云学术

THROMBOTIC THROMBOCYTOPENIC PURPURA (TTP) - AN UPDATED REVIEW

Published:2022-05-15 Issue: Volume: Page:120-121
ISSN:
Container-title:GLOBAL JOURNAL FOR RESEARCH ANALYSIS
language:en
Short-container-title:

Author:

Malik Parmila¹,Khajuria Atul²,Kumar Verma Mahendra³

Affiliation:

1. Ph.D. Scholar, Department of Medical Laboratory Technology, NIMS College Of Paramedical Technology

2. Ph.D. Medical Microbiology, Professor & H.O.D., Department of Medical Laboratory Technology, NIMS College Of Paramedical Technology.

3. Principal, NIMS College Of Paramedical Technology

Abstract

Thrombotic thrombocytopenic purpura is a microangiopathic hemolytic amenia characterized by fever, neurological dysfunction, renal dysfunction, thrombocytopenia, hemolytic anemia. TTP can be inherited or acquired, caused due to ADAMTS13 enzyme malfunctioning. As the condition is medical emergency timely treatment is essential and vital plasma exchange and chemotherapy are used to control the activities of the enzymes. The present article describes the causes, risk factors, diagnosis and standard treatment for the management of TTP.

Publisher

World Wide Journals

Reference14 articles.

1. Tanner L, Müller MM. [Blood Transfusion: a Guide to Clinical Decision Making]. Anasthesiol Intensivmed Notfallmed Schmerzther. 2019 Mar;54(3):194-205.

2. Coppo P, Cuker A, George JN. Thrombotic thrombocytopenic purpura: Toward targeted therapy and precision medicine. Res Pract Thromb Haemost. 2019 Jan;3(1):26-37.

3. Wiernek SL, Jiang B, Gustafson GM, Dai X. Cardiac implications of thrombotic thrombocytopenic purpura. World J Cardiol. 2018 Dec 26;10(12):254-266.

4. Cox EC. Thrombotic thrombocytopenic purpura: report of three additional cases and a short review of the literature. J S C Med Assoc. 1966 Dec;62(12):465-70.

5. Bell WR, Braine HG, Ness PM, Kickler TS. Improved survival in thrombotic thrombocytopenic purpura-hemolytic uremic syndrome. Clinical experience in 108 patients. N Engl J Med. 1991 Aug 08;325(6):398-403.