CLINICAL FEATURES AND VISUALACUITY OUTCOMES IN CULTUREPOSITIVE ENDOGENOUS ENDOPHTHALMITIS

Abstract

BACKGROUND:To report clinical features and treatment outcome in culture-positive endogenous endophthalmitis METHODS:All medical records with a clinical diagnosis of endogenous endophthalmitis from January 2011 to December 2017 presented at CL Gupta Eye Institute, Uttar Pradesh (India) were reviewed. Patients were included in the study if they had evidence of endogenous endophthalmitis in either eye, dened as the presence of iritis and vitritis on ophthalmic examination, and one or more of the following: positive vitreous culture, positive blood culture, or positive urine culture. RESULTS:Medical record of 41 patients diagnosed with EnE were reviewed. Mean follow-up of these patients was 17.9±7.5 months. Systemic disease preceded by EnE was present in 65.9% patients.History of Intravenous uid administration was present in 19 (46.3%) patients. Mean duration of disease from the date of presentation was 11.6±17.4 days.All EnE eyes secondary to fungal isolate had improvement in visual acuity, 42% EnE eyes secondary to bacterial isolate showed improvement, and vision was not improved in one EnE eyes with mixed infection.The logistic regression model explained that duration of illness in days (p=0.04) was signicantly associated with likelihood of favourable functional outcome. CONCLUSION: The endogenous endophthalmitis is generally associated with poor outcome.The prognosis depends on initial VA, duration of illness, and type of pathogen. The visual outcome suggest that the timely medical and surgical intervention can prevent loss of vision in cases of endogenous endophthalmitis.