PREVALENCE AND ANTIMICROBIAL SUSCEPTIBILITY PATTERN OF ACINETOBACTER SPECIES AMONG VARIOUS CLINICAL SAMPLES IN A TERTIARY CARE TEACHING HOSPITAL, SVIMS, TIRUPATHI.

Author:

Sneha P.1,Ramakrishna N.2,Jayaprada R.3,Sharma K.K.4

Affiliation:

1. Tutor, Dept of Microbiology

2. Assistant Professor, Dept of Microbiology, S.V. Institute of Medical Sciences, SVIMS University, Tirupathi, Andhra Pradesh, India.

3. Associate Professor, Dept of Microbiology, S.V. Institute of Medical Sciences, SVIMS University, Tirupathi, Andhra Pradesh, India.

4. Associate Professor& HOD I/C, Dept of Microbiology, S.V. Institute of Medical Sciences, SVIMS University, Tirupathi, Andhra Pradesh, India

Abstract

Multidrug resistance isolates of Acinetobacter sp. are increasing due to indiscriminate use of antibiotics in health care settings. The incidence of resistance to broad spectrum antibiotics is increasing and thus posing a therapeutic challenge. All samples were processed and isolates were identified as per standard protocol. 5Antibiotic susceptibility of all isolates was determined by the standard Kirby Bauer disc diffusion method as per Clinical laboratory standards institute (CLSI) guidelines 2017.6 Majority of the Acinetobacter sp. were isolated from E.T aspirates (47.3%). In our study A.baumannii (65.3%) was the most common species responsible for the infections. Among 150 Acinetobacter isolates, 68% of isolates were multidrug resistant organisms, 52% were extended spectrum beta-lactamase (ESBL) producers and 44% of isolates were carbapenem resistant. To abate antimicrobial resistance, antimicrobials ought to be prescribed sensibly and observational antimicrobial treatment ought to be resolved for every hospital as per institutional antibiogram. Strict adherence to the antibiotic policy and proper implementation of antibiotic stewardship program in coordination with clinicians can reduce emergence of multidrug resistant Acinetobacter species which is of great concern.

Publisher

World Wide Journals

Reference24 articles.

1. 1. Constatiniu S, Romaniuc A, Iancu LS, Filimon R, Tarasi I. Cultural and biochemical characteristics of Acinetobacter species strains isolated from hospital units. J. Prev. Med. 2004;12:35-42.

2. 2. Winn W, Allen S, Janda W, Koneman E, Procop G, et. al., Color Atlas and Textbook of Diagnostic Microbiology, 6th ed. 2006;353-62.

3. 3. Shareek PS, Kumar DS, Krishnan R, Subramanyan VR, Gafur KA, Thirunarayan MA. Antibiotic sensitivity pattern of blood isolates of Acinetobacterspecies . Am.J.Infect.Dis20128;2009;8:65-9.

4. 4. Chang HL, Tang HH, Hsu YM, Hsu , Lei wan, Fen chang Y, Lin CT, et. al., Nosocomial outbreak of infection with multidrug resistant Acinetobacterbaumanni. Infect control HospEpidemiol, 2009;30: 34-8.

5. 5. Collee, J. G., T. J. Mackie, and J. E. McCartney. Mackie & McCartney Practical Medical Microbiology. 18th ed. New York: Churchill Livingstone, 1996.

同舟云学术

1.学者识别学者识别

2.学术分析学术分析

3.人才评估人才评估

"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370

www.globalauthorid.com

TOP

Copyright © 2019-2024 北京同舟云网络信息技术有限公司
京公网安备11010802033243号  京ICP备18003416号-3