TO STUDY THE SIGNIFICANCE OF VARIOUS BIOCHEMICAL AND ND HEMATOLOGICAL PARAMETERS IN COVID CASES IN INDIA IN 2 WAVE OF COVID-19 PANDEMIC: STUDY FROM PUNE, MAHARASHTRA

Abstract

COVID -19 infection is an ongoing pandemic. The world has already witness two waves and a third one is imminent. Also the COVID 19 infection is now presenting with numerous manifestation besides respiratory symptom. Thus it becomes essential to study surrogate markers or various biochemical and hematological parameters and their signicance in these cases. Data available so far is mostly from other nations with only a limited number of studies from Indian context. Thus the present study was conducted to evaluate the signicance of laboratory parameters in predicting cases infected with COVID 19 and also the correlation of these parameters with gender and course of disease. 557 subjects were included in this study from Pune, Maharashtra. The groups were divided into cases and controls on basis of RT PCR results and clinical manifestations. The control group had 442 subjects and the cases were 135 in number. The inammatory markers (CRP, D-dimer and ferritin) were signicantly high in cases as compared to controls. Among cases 40 % patients belonged to young age (<45 years), 38% to middle age (45 -59 years) and 22 % to elderly group (>60 years). This shows high infectivity rate in st younger group as compared to 1 wave. NLR was higher in cases as compared to controls. CRP, D-dimer and ferritin were signicantly higher in cases as compared to controls