“ASSOCIATION OF LOWER URINARY TRACT SYMPTOMS WITH METABOLIC SYNDROME IN MALE PATIENTS OF AGE MORE THAN 45 YEARS.”

Abstract

Objective: The association of Lower Urinary Tract Symptoms with Metabolic Syndrome in male patients of age more than 45 years since there is insufcient data about LUTS and MetS in Indian population and contradicting reports in various studies regarding the correlation of LUTS and MetS worldwide. Methods- st st 152 men aged >45 years with symptoms of LUTS during a 365 period from 1 June 2019 to 31 May 2020 have been included in this observational study. LUTS were dened according to the International Prostate Symptom Score (IPSS) and metabolic syndrome with the National Cholesterol Education Program/Adult Treatment Panel III denition. We studied the correlation between metabolic syndrome and its individual components, and the severity of LUTS (IPSS and treatment for LUTS). Analyses were adjusted for body mass index, age, and prostate-specic antigen level. Results-. About one third of LUTS patients were between 60-69 years of age (33.6%), more than half moderate LUTS (65.8%)patients. Severe LUTS was most common in age ≥80 years (41.7%). MetS in LUTS patients was 33.6% highest in age 50- 59 years (42.1%) and was lowest in age ≥80 (16.7%). Prevalence of MetS in LUTS patients was 3.63 times higher in age 50-59 years than ≥80 years (OR=3.63, 95%CI=0.89-14.86). Conclusion- Our results suggest a signicant relationship between LUTS linked to benign prostatic hyperplasia and metabolic syndrome, in terms of frequency and severity. The risk of being treated for LUTS also increased with an increasing number of metabolic syndrome components present. The prevention of such modiable factors by the promotion of dietary changes and regular physical activity practice may be of great importance for public health.