A STUDY ON PROGNOSTIC VALUE OF SERUM CORTISOL IN STROKE AND ITS CORRELATION WITH NIHSS SCORE-Reference-Cited by-同舟云学术

A STUDY ON PROGNOSTIC VALUE OF SERUM CORTISOL IN STROKE AND ITS CORRELATION WITH NIHSS SCORE

Published:2023-02-01 Issue: Volume: Page:8-9
ISSN:
Container-title:INTERNATIONAL JOURNAL OF SCIENTIFIC RESEARCH
language:en
Short-container-title:ijsr

Author:

Ramesh Somineni¹,Siril Nandipati²,V. Chalapathi Rao K.³

Affiliation:

1. Postgraduate, Department of General Medicine, Alluri Sitarama Raju Academy of Medical Sciences, Eluru, West Godavari District, Andhra Pradesh 534005, India

2. Postgraduate, Department of General Medicine, Alluri Sitarama Raju Academy of Medical Sciences, Eluru, West Godavari District, Andhra Pradesh 534005, India.

3. Professor & HOD Department of General Medicine, Alluri Sitarama Raju Academy of Medical Sciences, Eluru, West Godavari District, Andhra Pradesh 534005, India

Abstract

Background: There are numerous clinical factors that have been identied as potential outcome predictors in patients with acute stroke, including symptom, severity, and advanced age. After an acute stroke, the hypothalamo-pituitary-adrenal (HPA) axis is activated as a result of the stress response. Abiomarker for predicting the outcome of an acute stroke is desperately needed. Aim and Objective:To assess the relationship of single serum cortisol level to the typeand severity of strokeand its correlation with NIHSS score. Methods: 100 new cases of stroke, within 72 hours of the onset, admitted in Alluri Sitarama Raju Academy of Medical Sciences from January 2021 to June 2022 were included in the study. CT Brain was taken to differentiate between ischemic and Haemorrhagic stroke. NIHSS (National Institute of Health Stroke Scale) score was assessed for severity. Serum cortisol levels were measured at admission. Correlation between serum cortisol levels and stroke scales were assessed. Results: Of the 100 cases,50 patients had ischemic(Group A), and 50 patients had hemorrhagic stroke(Group B). The Mean NIHSS score was signicantly higher in group B compared to group A(P<0.001).There was a statistically signicant correlation with raised serum cortisol levels and the severity of stroke irrespective of type of stroke P<0.001). Conclusion: In conclusion, serum cortisol is a prognostic indicator of severity of stroke. Serum cortisol level was found to have a signicant positive correlation with worse outcome of stroke

Publisher

World Wide Journals

Subject

History,Immunology,Immunology and Allergy,Pulmonary and Respiratory Medicine,Public Health, Environmental and Occupational Health,Health Policy,Law,Sociology and Political Science,Literature and Literary Theory,Linguistics and Language,Language and Linguistics,General Engineering,Literature and Literary Theory,Linguistics and Language,Language and Linguistics,Literature and Literary Theory,History,Cultural Studies,Political Science and International Relations

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