A Novel Approach to Increase Human Islet Cell Mass While Preserving β-Cell Function
Author:
Affiliation:
1. Department of Pediatrics and Surgery, The Whittier Institute, University of California at San Diego, La Jolla, California
2. Surgical Medical Research Institute, University of Alberta, Edmonton, Alberta, Canada
Abstract
Publisher
American Diabetes Association
Subject
Endocrinology, Diabetes and Metabolism,Internal Medicine
Link
https://journals.org/diabetes/diabetes/article-pdf/51/12/3435/652550/db1202003435.pdf
Reference26 articles.
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2. Hayek A, Beattie GM, Cirulli V, Lopez AD, Ricordi C, Rubin JS: Growth factor/matrix-induced proliferation of human adult β-cells. Diabetes 44:1458–1460,1995
3. Beattie GM, Cirulli V, Lopez AD, Hayek A: Ex vivo expansion of human pancreatic endocrine cells. J Clin Endocrinol Metab 82:1852–1856,1997
4. Halvorsen TL, Beattie GM, Lopez AD, Hayek A, Levine F: Accelerated telomere shortening and senescence in human pancreatic islet cells stimulated to divide in vitro. J Endocrinol 166:103–109,2000
5. Beattie GM, Itkin-Ansari P, Cirulli V, Leibowitz G, Lopez AD, Bossie S, Mally MI, Levine F, Hayek A: Sustained proliferation of PDX-1+ cells derived from human islets. Diabetes 48:1013–1019,1999
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